Simply innovative, this new nasal nebulization system (patent pending) minimizes penetration of aerosol in the pulmonary area, and increases the nasal and sino-nasal aerosol deposition.
- Really compliant nebulization system
- No patient participation
In vivo study
- Scintigraphic evaluation of the EASYNOSE nebulizer (B) in healthy volunteers with DTPA-Tc99m aerosol, in comparison with a standard sonic nasal jet-nebulizer (A).
| AEROSOL DEPOSITION | EASYNOSE | JET-NEBULIZER |
|---|---|---|
| Nasal cavities | 99 +/- 3% | 73 +/- 10% |
| Lungs | <1% | 27 +/- 10% |
- FOCUS: The 100 Hertz-sound technology of sonic nebulizer, in vivo evaluation
The addition of a 100 Hz-sound (sonic) during gas Krypton ventilation of nasal cavities modifies the distribution of the gas into the nasal cavities and allows its penetration into the maxillary sinuses.
Scientific communication
!NEW! Scintigraphy evaluation of the Easynose nasal nebuliser in a nasal cast model. Le Guellec S., Gatier S., Le Pennec D., Vullo F., Chantrel G., Vecellio L. DDL22, 2011. Poster PDF file
Deposition of aerosols delivered by nasal route with jet and mesh nebulizers. Vecellio L., De Gersem R., Le Guellec S., Reychler G., Pitance L., Le Pennec D., Diot P., Chantrel G., Bonfils P., Jamar F. Int J Pharm. 2011 Apr4;407(1-2): 87-94. Pubmed abstract
Deposition of aerosols delivered by nasal route with jet and mesh nebulizers. Vecellio L., De Gersem R., Le Guellec S., Reychler G., Pitance L., Le Pennec D., Diot P., Chantrel G., Bonfils P., Jamar F.
DDL21, 2010 with abstract available on JAM, 2011, 24(6):313-314. Poster PDF file
A new prototype nebulizer to optimize aerosol deposition into maxillary sinus and to limit lung deposition. Le Guellec S., Dubois F., Chantrel G., Charrouin L., Gatier S., Vecellio L. RDD, 2009. Poster PDF file
In the pipeline - Clinical study with the EASYNOSE nebulizer
MAY, 2011
The EASYNOSE has been selected for a phase III clinical study in patients with chronic rhinosinusitis (CRS patients).
The study is currently recruiting participant.